Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15486850 | 0.90 | BCL9 (0.48) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL6359040 | 0.90 | BCL9 (0.56) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL903436 | 0.90 | BCL9 (0.52) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL13073179 | 0.89 | BCL9 (0.47) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL15491284 | 0.89 | GAA (0.49) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL19112643 | 0.89 | BCL9 (0.47) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL6348206 | 0.88 | BCL9 (0.51) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL31488048 | 0.88 | BCL9 (0.51) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL2802479 | 0.88 | MGLL (0.57) | BCL9CTNNB1GAAHTR2AMGLL | |
| SCHEMBL15487706 | 0.88 | BCL9 (0.49) | BCL9CTNNB1GAAHTR2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8137700-B2 | Main chain acid-degradable polymers for the delivery of bioactive materials | U.S. DEPARTMENT OF ENERGY (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090220615-A1 | Main Chain Acid-Degradable Polymers for the Delivery of Bioactive Materials | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-09-03 | — | — | US | disclosed |
| EP-0395992-B1 | Radiosensitive polymer and positive working recording material | BASF AG (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5453341-A | Radiation-sensitive polymers and positive-working recording materials | SCHWALM REINHOLD (DE) | 1995-09-26 | — | — | US | disclosed |
| US-5260410-A | Photodegradation, semiconductor photoresists | SCHWALM REINHOLD (DE) | 1993-11-09 | — | — | US | disclosed |
| EP-0395992-A2 | Radiosensitive polymer and positive working recording material | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220615-A1 | Main Chain Acid-Degradable Polymers for the Delivery of Bioactive Materials | CTSA, GAA, CTSB | BCL9 2681/4885CTNNB1 4860/4885GAA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.