Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89448 | 0.81 | DAO (0.31) | DAOHCAR2 | |
| SCHEMBL89700 | 0.78 | USP2 (0.41) | DAO | |
| SCHEMBL89699 | 0.76 | MEN1 (0.38) | — | |
| SCHEMBL18067917 | 0.67 | HPGD (0.34) | DAO | |
| SCHEMBL28309864 | 0.66 | HPGD (0.38) | DAO | |
| SCHEMBL6901097 | 0.63 | ALDH1A1 (0.37) | DAO | |
| SCHEMBL23417378 | 0.61 | NPC1 (0.40) | DAO | |
| SCHEMBL5836886 | 0.60 | POLB (0.47) | — | |
| SCHEMBL6050776 | 0.60 | TYR (0.39) | — | |
| SCHEMBL20093101 | 0.58 | TLR7 (0.38) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420491-A1 | 3 , 5-substitued piperidine compounds as renin inhibitors | Novartis AG (CH) | 2012-02-22 | — | — | EP | disclosed |