Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
| ▸ | NOS1 | P29475 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987500 | 0.80 | ALDH1A1 (0.41) | S1PR3KDM4EALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL19003579 | 0.75 | KDM4E (0.40) | S1PR3KDM4EALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL25573950 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1CYP19A1HPGD | |
| SCHEMBL19464638 | 0.72 | KDM4E (0.46) | S1PR3KDM4EALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL19059398 | 0.71 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1CYP19A1HPGD | |
| SCHEMBL22363287 | 0.69 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1CYP19A1HPGD | |
| SCHEMBL21024658 | 0.68 | KDM4E (0.40) | PANK3S1PR3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4198843 | 0.65 | SKP2 (0.55) | SKP2KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL3467724 | 0.65 | CYP11B1 (0.47) | KDM4EALDH1A1L3MBTL1HPGDHTT | |
| SCHEMBL178452 | 0.64 | ALDH1A1 (0.50) | KDM4EALDH1A1CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190108-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V Biosciences, Inc. (US) | 2017-07-12 | — | — | EP | disclosed |