Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19118465 | 0.92 | PDE4B (0.66) | PDE4BPTGDR2PDE4DDGAT1 | |
| SCHEMBL16446595 | 0.88 | PDE4B (0.66) | PDE4BPTGDR2PDE4D | |
| SCHEMBL19119079 | 0.88 | PDE4B (0.71) | PDE4BPTGDR2PDE4D | |
| SCHEMBL16447019 | 0.86 | PDE4B (0.82) | PDE4BPTGDR2PDE4D | |
| SCHEMBL19119121 | 0.81 | PDE4B (0.53) | PDE4BPDE4DDGAT1 | |
| SCHEMBL19118469 | 0.80 | PDE4B (0.54) | PDE4B | |
| SCHEMBL19118473 | 0.80 | PDE4B (0.54) | PDE4BPDE4D | |
| SCHEMBL19119118 | 0.80 | PDE4B (0.51) | PDE4B | |
| SCHEMBL16446831 | 0.78 | PDE4B (0.53) | PDE4BPTGDR2PDE4DDGAT1 | |
| SCHEMBL16446717 | 0.77 | PDE4B (0.75) | PDE4BPTGDR2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030565-B1 | NOVEL SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2017-07-19 | — | — | EP | disclosed |