Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CPS1 | P31327 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19119463 | 0.91 | ROCK2 (0.48) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| Cyclohexane SCHEMBL19119453 | 0.90 | ROCK2 (0.50) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| Cyclopentane SCHEMBL19119283 | 0.90 | ROCK2 (0.50) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| SCHEMBL19119284 | 0.88 | ROCK2 (0.45) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| SCHEMBL19119378 | 0.86 | ROCK2 (0.44) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| SCHEMBL19119492 | 0.85 | ROCK2 (0.43) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| SCHEMBL354384 | 0.83 | ROCK2 (0.46) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| SCHEMBL354401 | 0.83 | ROCK2 (0.47) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| SCHEMBL354589 | 0.82 | ROCK2 (0.47) | ROCK2ROCK1ATG4BNPC1NAMPT | |
| SCHEMBL352913 | 0.81 | ROCK2 (0.48) | ROCK2ROCK1ATG4BNPC1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |