Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 16/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 15/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
| ▸ | DMPK | Q09013 | 1/20 | 0.39 |
| ▸ | MYLK | Q15746 | 1/20 | 0.39 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19119156 | 0.93 | ROCK1 (0.49) | ROCK1ROCK2EPHX2HSD17B13ATG4B | |
| SCHEMBL19119113 | 0.91 | ROCK2 (0.47) | ROCK1ROCK2EPHX2ATG4B | |
| SCHEMBL352559 | 0.87 | ROCK2 (0.50) | ROCK1ROCK2EPHX2HSD17B13ATG4B | |
| SCHEMBL19119187 | 0.84 | ROCK1 (0.48) | ROCK1ROCK2EPHX2ATG4B | |
| SCHEMBL19119157 | 0.83 | ROCK1 (0.51) | ROCK1ROCK2ATG4BSGK1AKT1 | |
| SCHEMBL19119292 | 0.83 | ROCK2 (0.51) | ROCK1ROCK2EPHX2ATG4B | |
| SCHEMBL19118770 | 0.83 | ROCK2 (0.49) | ROCK1ROCK2EPHX2HSD17B13ATG4B | |
| SCHEMBL19119270 | 0.83 | ROCK2 (0.50) | ROCK1ROCK2EPHX2ATG4B | |
| SCHEMBL19118739 | 0.82 | ROCK1 (0.51) | ROCK1ROCK2ATG4BSGK1AKT1 | |
| SCHEMBL19119382 | 0.82 | ROCK1 (0.48) | ROCK1ROCK2EPHX2ATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |