Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 5/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248493 | 0.88 | HDAC1 (0.53) | WNT3AKDM1AHDAC1PSEN1PSEN2 | |
| SCHEMBL248751 | 0.75 | PSEN1 (0.59) | WNT3AKDM1AHDAC1PSEN1PSEN2 | |
| SCHEMBL1912409 | 0.68 | PDE3B (0.45) | WNT3A | |
| SCHEMBL1912406 | 0.68 | HDAC2 (0.50) | WNT3AHDAC1MAPK1 | |
| SCHEMBL12699626 | 0.67 | WNT3A (0.54) | WNT3A | |
| SCHEMBL27971540 | 0.66 | WNT3A (0.52) | WNT3A | |
| SCHEMBL15607097 | 0.64 | WNT3A (0.76) | WNT3A | |
| SCHEMBL15606943 | 0.63 | WNT3A (0.69) | WNT3A | |
| SCHEMBL14802584 | 0.63 | HDAC1 (0.51) | KDM1AHDAC1MAPK1 | |
| SCHEMBL246715 | 0.63 | WNT3A (0.61) | WNT3APSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003189-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE WNT SIGNALING PATHWAY | IRM LLC (BM) | 2012-01-05 | — | — | WO | disclosed |