Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.76 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16888269 | 1.00 | RORC (0.76) | RORCNR1I2NR1H3 | |
| SCHEMBL18204929 | 1.00 | RORC (0.76) | RORCNR1I2NR1H3 | |
| SCHEMBL18204897 | 0.93 | RORC (0.78) | RORCNR1I2NR1H3 | |
| SCHEMBL18204872 | 0.88 | RORC (0.80) | RORCNR1I2NR1H3 | |
| SCHEMBL16891742 | 0.88 | RORC (0.80) | RORCNR1I2NR1H3 | |
| SCHEMBL18213858 | 0.88 | RORC (0.80) | RORCNR1I2NR1H3 | |
| SCHEMBL16888273 | 0.88 | RORC (0.75) | RORCNR1I2 | |
| SCHEMBL18204928 | 0.88 | RORC (0.75) | RORCNR1I2 | |
| Hydrochloric Acid SCHEMBL18204937 | 0.87 | RORC (0.73) | RORCNR1I2 | |
| Hydrochloric Acid SCHEMBL16876991 | 0.87 | RORC (0.73) | RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708253-B2 | Cyclohexyl sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708253-B2 | Cyclohexyl sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |