Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15937172 | 0.95 | JAK3 (0.33) | JAK3 | |
| SCHEMBL17359172 | 0.95 | JAK3 (0.33) | JAK3 | |
| SCHEMBL17359164 | 0.92 | — | — | |
| SCHEMBL15937215 | 0.86 | GRIN2B (0.32) | — | |
| SCHEMBL15937177 | 0.86 | GRIN2B (0.32) | — | |
| SCHEMBL17359167 | 0.86 | — | — | |
| SCHEMBL19129085 | 0.84 | JAK3 (0.33) | JAK3 | |
| SCHEMBL17351832 | 0.82 | GRIN2B (0.47) | JAK3 | |
| SCHEMBL17359171 | 0.82 | GRIN2B (0.47) | JAK3 | |
| SCHEMBL15937153 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708335-B2 | Spiro-lactam NMDA receptor modulators and uses thereof | Apytinyx Inc. (US) | 2017-07-18 | — | — | US | disclosed |