Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 7/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15937101 | 0.94 | GRIN2B (0.41) | IL1RNERAP2ERAP1ELANECTSL | |
| SCHEMBL17351809 | 0.94 | GRIN2B (0.41) | IL1RNERAP2ERAP1ELANECTSL | |
| SCHEMBL15937244 | 0.91 | IL1RN (0.36) | IL1RNERAP2ERAP1LMNA | |
| SCHEMBL20126641 | 0.91 | IL1RN (0.36) | IL1RNERAP2ERAP1LMNA | |
| SCHEMBL17351899 | 0.91 | IL1RN (0.36) | IL1RNERAP2ERAP1LMNA | |
| SCHEMBL19129091 | 0.86 | GRIN2B (0.37) | ELANELMNA | |
| SCHEMBL15937085 | 0.86 | CCR1 (0.40) | IL1RNERAP2ERAP1CTSLCTSB | |
| SCHEMBL17356203 | 0.85 | ALDH1A1 (0.39) | — | |
| SCHEMBL17359168 | 0.83 | CYP2C19 (0.42) | — | |
| SCHEMBL20126625 | 0.82 | GRIN2B (0.39) | ELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708335-B2 | Spiro-lactam NMDA receptor modulators and uses thereof | Apytinyx Inc. (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708335-B2 | Spiro-lactam NMDA receptor modulators and uses thereof | Apytinyx Inc. (US) | 2017-07-18 | — | — | US | disclosed |