Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17590831 | 0.92 | NPC1 (0.35) | NPC1RAB9ATSHRMAP3K5DGAT1 | |
| SCHEMBL17590832 | 0.86 | NPC1 (0.35) | NPC1RAB9ATSHRMAP3K5DGAT1 | |
| SCHEMBL14904668 | 0.86 | NPC1 (0.37) | NPC1RAB9ATSHRMAP3K5DGAT1 | |
| SCHEMBL14904688 | 0.86 | NPC1 (0.39) | NPC1RAB9ADGAT1ALDH1A1GAA | |
| SCHEMBL14904642 | 0.83 | NPC1 (0.39) | NPC1RAB9ADGAT1ALDH1A1MAPK1 | |
| SCHEMBL14904607 | 0.83 | NPC1 (0.35) | NPC1RAB9AMAP3K5DGAT1ALDH1A1 | |
| SCHEMBL16269903 | 0.83 | NPC1 (0.36) | NPC1RAB9ATSHRMAP3K5DGAT1 | |
| SCHEMBL4968689 | 0.82 | NPC1 (0.34) | NPC1RAB9ATSHRMAP3K5DGAT1 | |
| SCHEMBL2690089 | 0.82 | ALDH1A1 (0.32) | NPC1RAB9AMAP3K5DGAT1ALDH1A1 | |
| SCHEMBL10278778 | 0.82 | NPC1 (0.35) | NPC1RAB9ATSHRDGAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |