Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919598 | 0.81 | ESR1 (0.44) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL9766362 | 0.79 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL12160321 | 0.77 | ESR1 (0.41) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL12979079 | 0.77 | ESR1 (0.41) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL12979782 | 0.77 | ESR1 (0.41) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL2918704 | 0.75 | NR1H2 (0.40) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL15800382 | 0.75 | NR1H2 (0.40) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL10387746 | 0.75 | NR1H2 (0.40) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL4619514 | 0.74 | NR1H2 (0.39) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL10486795 | 0.74 | NR1H2 (0.39) | NR1H2NR1H3ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944772-B2 | Organosiloxane, curable silicone composition, and semiconductor device | DOW CORNING TORAY CO., LTD. (JP) | 2018-04-17 | — | — | US | disclosed |
| US-20170204252-A1 | Organosiloxane, Curable Silicone Composition, And Semiconductor Device | DOW TORAY CO., LTD. (JP) | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204252-A1 | Organosiloxane, Curable Silicone Composition, And Semiconductor Device | SMCHD1, CD99, CDYL | NR1H2 1914/4885NR1H3 1769/4885ESR1 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.