Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121943 | 0.95 | CASR (0.35) | CASRUTS2RDDB1CRBNTDP1 | |
| SCHEMBL19133984 | 0.95 | CASR (0.35) | CASRUTS2RDDB1CRBNTDP1 | |
| SCHEMBL19133980 | 0.93 | CASR (0.41) | CASRTDP1KMT2ANPC1RAB9A | |
| SCHEMBL479566 | 0.90 | CASR (0.40) | CASRTDP1L3MBTL1TP53POLB | |
| SCHEMBL19133982 | 0.89 | MAPT (0.41) | CASRTDP1KMT2ANPC1RAB9A | |
| SCHEMBL3844906 | 0.87 | KMT2A (0.39) | DDB1CRBNTDP1L3MBTL1TP53 | |
| SCHEMBL2117916 | 0.87 | RAB9A (0.38) | CASRTDP1L3MBTL1TP53POLB | |
| SCHEMBL479599 | 0.87 | TP53 (0.36) | CASRTDP1L3MBTL1TP53POLB | |
| SCHEMBL480691 | 0.86 | RAB9A (0.37) | CASRTDP1L3MBTL1TP53POLB | |
| SCHEMBL480642 | 0.86 | KMT2A (0.39) | CASRTDP1L3MBTL1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-B1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |