Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430972 | 0.85 | PIK3CD (0.66) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL7649491 | 0.83 | PIK3CD (0.58) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL20886713 | 0.81 | PIK3CD (0.56) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL22004101 | 0.81 | PIK3CD (0.51) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL21207378 | 0.80 | PIK3CD (0.55) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL12197894 | 0.79 | PIK3CD (0.58) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL22600522 | 0.79 | PIK3CD (0.53) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL1705435 | 0.79 | PIK3CD (0.53) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL22021621 | 0.79 | PIK3CD (0.53) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL104477 | 0.78 | PIK3CD (0.61) | PIK3CDKMT2AMEN1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102616-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-9708337-B2 | Aryl amide-based kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |