Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732459 | 0.95 | PIK3CD (0.47) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL4336427 | 0.89 | PIK3CD (0.49) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL21207378 | 0.88 | PIK3CD (0.55) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL1980364 | 0.87 | PIK3CD (0.47) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL21009232 | 0.84 | PIK3CD (0.65) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL26855476 | 0.84 | PIK3CD (0.65) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL5499961 | 0.83 | PIK3CD (0.50) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL28358784 | 0.83 | PIK3CD (0.42) | PIK3CDKMT2AMEN1PKM | |
| SCHEMBL5914541 | 0.83 | PIK3CD (0.49) | PIK3CDKMT2AMEN1PKMLMNA | |
| SCHEMBL3430972 | 0.82 | PIK3CD (0.66) | PIK3CDKMT2AMEN1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192879-B2 | Chemokine receptor modulators and uses thereof | RAPT THERAPEUTICS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200339539-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339539-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | ACKR3, CCR5, CXCR3 | PIK3CD 3482/4885KMT2A 4733/4885MEN1 4813/4885 |
| US-11192879-B2 | Chemokine receptor modulators and uses thereof | ACKR3, CCR5, CXCR3 | PIK3CD 3482/4885KMT2A 4733/4885MEN1 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.