⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633170 | 0.82 | — | — | |
| SCHEMBL4196710 | 0.69 | — | — | |
| SCHEMBL9795348 | 0.65 | — | — | |
| SCHEMBL21937200 | 0.64 | L3MBTL1 (0.45) | — | |
| SCHEMBL21126667 | 0.64 | KDM4E (0.61) | — | |
| SCHEMBL10394042 | 0.62 | — | — | |
| SCHEMBL21127191 | 0.61 | KDM4E (0.50) | — | |
| SCHEMBL21126653 | 0.60 | CCR1 (0.61) | — | |
| SCHEMBL21126500 | 0.60 | NPC1 (0.50) | — | |
| SCHEMBL21737335 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005676-A1 | ENHANCING THE THERAPEUTIC EFFECT OF ACUPUNCTURE WITH ADENOSINE | UNIVERSITY OF ROCHESTER (US) | 2013-01-03 | — | — | US | disclosed |
| EP-2504347-A1 | ENHANCING THE THERAPEUTIC EFFECT OF ACUPUNCTURE WITH ADENOSINE | University Of Rochester (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011066412-A1 | ENHANCING THE THERAPEUTIC EFFECT OF ACUPUNCTURE WITH ADENOSINE | UNIVERSITY OF ROCHESTER (US) | 2011-06-03 | — | — | WO | disclosed |
| US-20100284984-A1 | ADENOSINE AND ITS MIMETICS. MODULATORS, TRANSPORT INHIBITORS, AND RECEPTOR AGONISTS AS A THERAPEUTIC TOOL TO REPLACE OR IMPROVE THE EFFICACY OF DEEP BRAIN STIMULATION | UNIVERSITY OF ROCHESTER (US) | 2010-11-11 | — | — | US | disclosed |
| EP-2180916-A1 | ADENOSINE AND ITS MIMETICS, MODULATORS, TRANSPORT INHIBITORS, AND RECEPTOR AGONISTS AS A THERAPEUTIC TOOL TO REPLACE OR IMPROVE THE EFFICACY OF DEEP BRAIN STIMULATION | University Of Rochester (US) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009018275-A1 | ADENOSINE AND ITS MIMETICS, MODULATORS, TRANSPORT INHIBITORS, AND RECEPTOR AGONISTS AS A THERAPEUTIC TOOL TO REPLACE OR IMPROVE THE EFFICACY OF DEEP BRAIN STIMULATION | UNIVERSITY OF ROCHESTER (US) | 2009-02-05 | — | — | WO | disclosed |
| EP-0724587-B1 | RING-EXPANDED NUCLEOSIDES AND NUCLEOTIDES | NABI (US) | 2002-09-04 | — | — | EP | disclosed |