Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB7A | P51149 | 2/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19326206 | 0.91 | RAB7A (0.55) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19321379 | 0.90 | RAB7A (0.55) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19326303 | 0.89 | RAB7A (0.53) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19321407 | 0.89 | RAB7A (0.55) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19140455 | 0.86 | RAB7A (0.61) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19140838 | 0.82 | RAB7A (0.53) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19141650 | 0.82 | RAB7A (0.57) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19140926 | 0.81 | RAB7A (0.56) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19325820 | 0.80 | RAB7A (0.54) | RAB7AKIF11MEN1KMT2ANPC1 | |
| SCHEMBL19141324 | 0.79 | RAB7A (0.55) | RAB7AKIF11MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192794-A1 | SUSTAINED HIV PROTEASE INHIBITOR | Shionogi & Co., Ltd. (JP) | 2017-07-19 | — | — | EP | disclosed |