Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | GPR39 | O43194 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19142435 | 0.95 | PLAU (0.38) | MAPTGAALMNATP53SMN1; SMN2 | |
| SCHEMBL19139313 | 0.86 | MAPT (0.39) | MAPTGAALMNATP53SMN1; SMN2 | |
| SCHEMBL22328736 | 0.85 | NPC1 (0.38) | MAPTLMNATP53SMN1; SMN2CYP3A4 | |
| SCHEMBL23049326 | 0.85 | NPC1 (0.38) | MAPTTP53SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL19139336 | 0.80 | HDAC8 (0.38) | MAPTGAALMNATP53SMN1; SMN2 | |
| SCHEMBL22328720 | 0.79 | MAPT (0.39) | MAPTGAALMNATP53SMN1; SMN2 | |
| SCHEMBL22328700 | 0.79 | HDAC8 (0.39) | MAPTALDH1A1HPGD | |
| SCHEMBL22328707 | 0.78 | CES2 (0.37) | MAPTLMNASMN1; SMN2POLBMAOB | |
| SCHEMBL19142681 | 0.77 | SMN1; SMN2 (0.36) | MAPTSMN1; SMN2POLBMAOAMAOB | |
| SCHEMBL19216995 | 0.76 | PLAU (0.40) | MAPTTP53SMN1; SMN2PLAUCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192847-A1 | ORGANIC LIGHT EMITTING DIODE | LG Chem, Ltd. (KR) | 2017-07-19 | — | — | EP | disclosed |