Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19127388 | 0.86 | GPR119 (0.54) | GPR119GRM1GRM5HTTATM | |
| SCHEMBL19126721 | 0.85 | GPR119 (0.58) | GPR119GRM1GRM5HTTATM | |
| SCHEMBL19126753 | 0.84 | GPR119 (0.52) | GPR119GRM1GRM5HTTATM | |
| SCHEMBL19126554 | 0.83 | GPR119 (0.51) | GPR119GRM1GRM5HTTATM | |
| SCHEMBL19126818 | 0.82 | GPR119 (0.48) | GPR119GRM1GRM5HTTATM | |
| SCHEMBL19126500 | 0.81 | GPR119 (0.49) | GPR119GRM1GRM5HTTATM | |
| SCHEMBL19145401 | 0.81 | GPR119 (0.49) | GPR119GRM1GRM5 | |
| SCHEMBL20676167 | 0.81 | GPR119 (0.58) | GPR119GRM1GRM5CA12CA1 | |
| SCHEMBL19126575 | 0.80 | GPR119 (0.48) | GPR119GRM1GRM5HTTATM | |
| SCHEMBL19126487 | 0.79 | EPHX2 (0.49) | GPR119GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121444-A1 | QUINOLIN-2-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-07-20 | — | — | WO | disclosed |