Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | NPEPPS | P55786 | 3/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16822303 | 0.87 | HINT1 (0.48) | HINT1HPGDADORA3ADORA2AADORA2B | |
| SCHEMBL19035636 | 0.87 | HINT1 (0.48) | HINT1HPGDADORA3ADORA2AADORA2B | |
| SCHEMBL16822302 | 0.87 | HINT1 (0.48) | HINT1HPGDADORA3ADORA2AADORA2B | |
| SCHEMBL16840864 | 0.87 | HINT1 (0.48) | HINT1HPGDADORA3ADORA2AADORA2B | |
| SCHEMBL19127168 | 0.86 | TYMP (0.47) | HINT1HPGDNT5EACHEADORA1 | |
| SCHEMBL19146315 | 0.86 | HINT1 (0.55) | HINT1HPGDNT5EADORA3ADORA2A | |
| SCHEMBL21253088 | 0.85 | HPGD (0.49) | HINT1HPGDADORA3ADORA2AADORA2B | |
| SCHEMBL21253092 | 0.85 | HPGD (0.49) | HINT1HPGDADORA3ADORA2AADORA2B | |
| SCHEMBL19145875 | 0.84 | HPGD (0.39) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL7708529 | 0.80 | HPGD (0.39) | HINT1HPGDNT5EADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017123669-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | GLICK GARY (US) | 2017-07-20 | — | — | WO | disclosed |