Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14584210 | 0.88 | NPSR1 (0.58) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL27956749 | 0.84 | CPT1A (0.49) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL31693410 | 0.82 | TP53 (0.67) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL18499262 | 0.80 | SMN1; SMN2 (0.76) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14595187 | 0.80 | LMNA (0.53) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14595227 | 0.78 | POLB (0.54) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL2492048 | 0.78 | LMNA (0.64) | LMNAHTTGAA | |
| SCHEMBL14595221 | 0.78 | CPT1A (0.60) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL19146889 | 0.78 | MAPT (0.55) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL27956740 | 0.77 | CPT1A (0.51) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017123826-A1 | MAST-CELL MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2017-07-20 | — | — | WO | disclosed |