Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199967 | 0.91 | CASP2 (0.91) | CASP2NAAAMEN1KMT2AFAAH | |
| SCHEMBL27137140 | 0.90 | CASP2 (0.74) | CASP2KDM4EMAPK1HIF1ANAAA | |
| SCHEMBL22211311 | 0.90 | CASP2 (0.68) | CASP2KDM4EMAPK1HIF1ANAAA | |
| SCHEMBL16072836 | 0.89 | CASP2 (0.59) | CASP2KDM4EMAPK1HIF1ANAAA | |
| SCHEMBL7537764 | 0.89 | CASP2 (0.86) | CASP2NAAAMEN1KMT2AFAAH | |
| SCHEMBL19960974 | 0.88 | CASP2 (0.71) | CASP2KDM4EMAPK1HIF1ANAAA | |
| SCHEMBL19960886 | 0.88 | CASP2 (0.71) | CASP2KDM4EMAPK1HIF1ANAAA | |
| SCHEMBL2497062 | 0.87 | CASP2 (1.00) | CASP2NAAAFAAHDNM1EPHX1 | |
| SCHEMBL9795571 | 0.87 | CASP2 (1.00) | CASP2NAAAFAAHDNM1EPHX1 | |
| SCHEMBL10149803 | 0.87 | CASP2 (1.00) | CASP2NAAAFAAHDNM1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
| US-20170202217-A1 | ANTIBACTERIAL POLYMER, PRODUCTION METHOD THEREFOR, AND USAGE THEREOF | NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY (JP) | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202217-A1 | ANTIBACTERIAL POLYMER, PRODUCTION METHOD THEREFOR, AND USAGE THEREOF | WASF2, HASPIN, MRPL21 | CASP2 1579/4885KDM4E 3467/4885MAPK1 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.