Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17791881 | 0.72 | SLC1A3 (0.47) | KMT2AL3MBTL1KDM4C | |
| SCHEMBL12786644 | 0.68 | KMT2A (0.42) | KMT2AL3MBTL1KDM4CP2RX7MAPK1 | |
| SCHEMBL1915970 | 0.67 | CPA3 (0.56) | KEAP1 | |
| SCHEMBL31477163 | 0.67 | POLB (0.45) | KMT2AL3MBTL1POLBKDM4CMAPK1 | |
| SCHEMBL1916048 | 0.67 | KMT2A (0.49) | KMT2A | |
| SCHEMBL29675373 | 0.67 | KMT2A (0.47) | KMT2AL3MBTL1KDM4C | |
| SCHEMBL20738685 | 0.67 | KMT2A (0.41) | KMT2AL3MBTL1KDM4CP2RX7FNTA | |
| SCHEMBL1914508 | 0.66 | KMT2A (0.37) | KMT2AL3MBTL1POLBKDM4CP2RX7 | |
| SCHEMBL28020490 | 0.66 | MAPK1 (0.46) | KMT2AL3MBTL1KDM4CMAPK1 | |
| SCHEMBL31326469 | 0.66 | NAPRT (0.54) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076734-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATORY DISEASES | EUROSCREEN S.A. (BE) | 2011-06-30 | — | — | WO | disclosed |