Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 19/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766651 | 0.95 | OPRL1 (0.49) | OPRM1OPRL1OPRK1 | |
| SCHEMBL21766728 | 0.83 | OPRL1 (0.52) | OPRM1OPRL1OPRK1 | |
| SCHEMBL22540296 | 0.82 | OPRL1 (0.52) | OPRM1OPRL1OPRK1 | |
| SCHEMBL19154112 | 0.81 | OPRM1 (0.46) | OPRM1OPRL1OPRK1 | |
| SCHEMBL19153829 | 0.79 | OPRM1 (0.50) | OPRM1OPRL1 | |
| SCHEMBL19151119 | 0.79 | OPRM1 (0.58) | OPRM1OPRL1OPRK1 | |
| SCHEMBL22540261 | 0.78 | OPRM1 (0.46) | OPRM1OPRL1 | |
| SCHEMBL19153839 | 0.77 | OPRM1 (0.49) | OPRM1OPRL1 | |
| SCHEMBL19145225 | 0.76 | OPRM1 (0.53) | OPRM1OPRL1 | |
| SCHEMBL23316766 | 0.76 | OPRL1 (0.42) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121650-A1 | 8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2017-07-20 | — | — | WO | disclosed |