Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19094417 | 0.59 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19094418 | 0.59 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19116454 | 0.59 | OPRM1 (0.70) | OPRM1OPRL1 | |
| SCHEMBL7773649 | 0.54 | HDAC1 (0.62) | LMNAHPGD | |
| SCHEMBL20054844 | 0.54 | MME (0.39) | OPRM1OPRL1SLC6A2 | |
| SCHEMBL6228602 | 0.54 | OPRM1 (0.40) | OPRM1OPRL1SLC6A2SLC6A4 | |
| SCHEMBL29156157 | 0.54 | ESR1 (0.39) | OPRM1KDM4ELMNASLC6A2SLC6A4 | |
| SCHEMBL7773734 | 0.54 | HDAC1 (0.61) | LMNAMEN1HPGDKMT2A | |
| SCHEMBL27262560 | 0.54 | SLC6A4 (0.46) | OPRM1OPRL1SLC6A2SLC6A4 | |
| SCHEMBL13849911 | 0.53 | OPRM1 (0.44) | OPRM1OPRL1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121646-A1 | 3-(CARBOXYETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2017-07-20 | — | — | WO | disclosed |