Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.81 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19094352 | 0.89 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19111107 | 0.89 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19094350 | 0.89 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19094402 | 0.89 | OPRM1 (0.86) | OPRM1OPRL1 | |
| SCHEMBL19111019 | 0.89 | OPRM1 (0.86) | OPRM1OPRL1 | |
| SCHEMBL19094405 | 0.89 | OPRM1 (0.86) | OPRM1OPRL1 | |
| SCHEMBL22503847 | 0.87 | OPRM1 (0.80) | OPRM1OPRL1 | |
| SCHEMBL19097209 | 0.85 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19097208 | 0.85 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19106749 | 0.85 | OPRM1 (1.00) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121646-A1 | 3-(CARBOXYETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2017-07-20 | — | — | WO | disclosed |