Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426843 | 0.89 | FFAR4 (0.65) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL19154981 | 0.88 | FFAR1 (0.56) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL12301123 | 0.83 | RXRA (0.63) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL1219328 | 0.82 | FFAR1 (0.51) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6832641 | 0.79 | FFAR1 (0.49) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL13069269 | 0.79 | FFAR1 (0.49) | FFAR4FFAR1ALDH1A1LMNAHTT | |
| SCHEMBL22381399 | 0.76 | BRD4 (0.52) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL22275893 | 0.76 | FFAR1 (0.48) | FFAR4FFAR1MEN1KMT2ALMNA | |
| SCHEMBL4749281 | 0.76 | FFAR1 (0.47) | FFAR4FFAR1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL13069271 | 0.76 | FFAR1 (0.47) | FFAR4FFAR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714230-B2 | Histone demethylase inhibitors | Celgene Quantical Research, Inc. (US) | 2017-07-25 | — | — | US | disclosed |