Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21663329 | 1.00 | POLB (0.37) | POLBAPEX1HTTTDP1BACE1 | |
| SCHEMBL15495194 | 0.96 | POLB (0.40) | POLBAPEX1HTTTDP1BACE1 | |
| SCHEMBL20343011 | 0.93 | BACE1 (0.42) | POLBAPEX1HTTTDP1BACE1 | |
| SCHEMBL21004634 | 0.90 | RARG (0.37) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19158936 | 0.90 | RARG (0.37) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19156792 | 0.90 | POLB (0.36) | POLBAPEX1HTTTDP1BACE1 | |
| SCHEMBL22537030 | 0.90 | HTT (0.38) | POLBAPEX1HTTTDP1BACE1 | |
| SCHEMBL19497312 | 0.89 | BACE1 (0.45) | POLBAPEX1HTTTDP1BACE1 | |
| SCHEMBL21559762 | 0.89 | POLB (0.35) | POLBAPEX1HTTTDP1BACE1 | |
| SCHEMBL22537031 | 0.89 | POLB (0.35) | POLBAPEX1HTTTDP1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881383-B1 | Mixing device and its use | MERCK PATENT GMBH (DE) | 2020-06-24 | — | — | EP | disclosed |
| EP-3428246-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-04-15 | — | — | EP | disclosed |
| EP-3234689-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-01-29 | — | — | EP | disclosed |
| EP-3083408-B1 | FILLING DEVICE AND USE THEREOF FOR FILLING A FLUID | MERCK PATENT GMBH (DE) | 2018-02-21 | — | — | EP | disclosed |
| EP-2837671-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-2993216-B1 | COMPOUNDS AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |