Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20343011 | 0.97 | BACE1 (0.42) | BACE1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL20428197 | 0.93 | BACE1 (0.39) | BACE1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15495194 | 0.91 | POLB (0.40) | BACE1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL21663329 | 0.89 | POLB (0.37) | BACE1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL19157295 | 0.89 | POLB (0.37) | BACE1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL18494395 | 0.89 | HTT (0.41) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL18699652 | 0.88 | POLB (0.38) | BACE1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL20428196 | 0.87 | POLB (0.37) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL19683314 | 0.86 | ELANE (0.38) | BACE1FFAR1POLBAPEX1HTT | |
| SCHEMBL19497715 | 0.85 | CTSA (0.43) | CYP2C19APPFFAR1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489329-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-12 | — | — | EP | disclosed |
| EP-3660128-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2020-06-03 | — | — | EP | disclosed |
| EP-3489329-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-2886627-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |
| EP-3067406-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |
| EP-3428246-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2019-01-16 | — | — | EP | disclosed |
| EP-3083883-B1 | METHOD FOR CLEANING A LIQUID CRYSTAL MIXTURE | MERCK PATENT GMBH (DE) | 2018-07-11 | — | — | EP | disclosed |
| EP-2703472-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2018-07-04 | — | — | EP | disclosed |
| EP-2837671-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2017-10-25 | — | — | EP | disclosed |