Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158945 | 0.92 | MAPK13 (0.34) | — | |
| SCHEMBL17503804 | 0.72 | KDM4C (0.41) | KDM4ETSHR | |
| SCHEMBL20550782 | 0.69 | KDM4C (0.39) | KDM4ETSHR | |
| SCHEMBL20243693 | 0.66 | TSHR (0.35) | KDM4ETSHR | |
| SCHEMBL17503779 | 0.62 | KDM5B (0.41) | — | |
| SCHEMBL17503744 | 0.62 | KDM2B (0.39) | — | |
| SCHEMBL31612490 | 0.59 | SIGMAR1 (0.55) | KDM4ETSHRTMEM97SIGMAR1 | |
| SCHEMBL17917694 | 0.58 | SIGMAR1 (0.54) | KDM4ETSHRTMEM97SIGMAR1 | |
| SCHEMBL9131306 | 0.58 | TMEM97 (0.56) | KDM4ETSHRTMEM97SIGMAR1 | |
| SCHEMBL7855918 | 0.58 | SIGMAR1 (0.51) | KDM4ETSHRTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |