Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18511710 | 0.99 | NR4A2 (0.39) | NR4A2DHODHPOLBAPEX1HTT | |
| SCHEMBL16559845 | 0.96 | POLB (0.40) | NR4A2DHODHPOLBAPEX1HTT | |
| SCHEMBL16559830 | 0.94 | POLB (0.41) | NR4A2DHODHPOLBAPEX1HTT | |
| SCHEMBL19159050 | 0.92 | NR4A2 (0.40) | NR4A2DHODHFFAR1EGFRRARA | |
| SCHEMBL16559831 | 0.92 | POLB (0.39) | NR4A2DHODHPOLBAPEX1HTT | |
| SCHEMBL16559834 | 0.89 | POLB (0.45) | POLBAPEX1HTTTDP1FFAR1 | |
| SCHEMBL24440947 | 0.89 | POLB (0.47) | POLBAPEX1HTTTDP1FFAR1 | |
| SCHEMBL16559860 | 0.88 | POLB (0.37) | POLBAPEX1HTTTDP1FFAR1 | |
| SCHEMBL18437009 | 0.88 | EGFR (0.40) | NR4A2DHODHPOLBAPEX1HTT | |
| SCHEMBL18511197 | 0.88 | EGFR (0.40) | NR4A2DHODHPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848676-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |