SCHEMBL16559830

SCHEMBL16559830

C=C(C)C(=O)OCCOc1cc(OCCOC(=O)C(=C)C)cc(-c2ccc(OC(=O)C(=C)C)c(F)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.41
▸ APEX1 P27695 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ THRB P10828 1/20 0.38
▸ RARA P10276 1/20 0.37
▸ RARB P10826 1/20 0.37
▸ FAAH O00519 2/20 0.35
▸ FFAR4 Q5NUL3 2/20 0.34
▸ AAK1 Q2M2I8 2/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CSF3R Q99062 1/20 0.33
▸ NR4A2 P43354 1/20 0.33
▸ DHODH Q02127 1/20 0.33
▸ FFAR1 O14842 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ ERN1 O75460 1/20 0.33
▸ TSHR P16473 2/20 0.32
▸ LTB4R Q15722 1/20 0.32
▸ CYP17A1 P05093 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16559845 0.99 POLB (0.40) POLBAPEX1HTTTDP1THRB
SCHEMBL16559831 0.98 POLB (0.39) POLBAPEX1HTTTDP1THRB
SCHEMBL18511710 0.96 NR4A2 (0.39) POLBAPEX1HTTTDP1THRB
SCHEMBL19159161 0.94 NR4A2 (0.38) POLBAPEX1HTTTDP1THRB
SCHEMBL16559834 0.94 POLB (0.45) POLBAPEX1HTTTDP1THRB
SCHEMBL19159115 0.93 POLB (0.36) POLBAPEX1HTTTDP1THRB
SCHEMBL22353022 0.92 POLB (0.37) POLBAPEX1HTTTDP1THRB
SCHEMBL24440947 0.92 POLB (0.47) POLBAPEX1HTTTDP1THRB
SCHEMBL21115722 0.91 POLB (0.37) POLBAPEX1HTTTDP1THRB
SCHEMBL21087449 0.91 POLB (0.35) POLBAPEX1HTTTDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 — — US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 — — US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 — — EP disclosed
WO-2024132893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 — — WO disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 — — WO disclosed
WO-2024126567-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-20 — — WO disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 — — US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 — — US disclosed
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 — — EP disclosed
EP-4306614-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2024-01-17 — — EP disclosed
US-20170037315-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-09 — — US disclosed
EP-3127989-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-02-08 — — EP disclosed
US-9487702-B2 Liquid crystal medium MERCK PATENT GMBH (DE) 2016-11-08 — — US disclosed
US-9487702-B2 Liquid crystal medium MERCK PATENT GMBH (DE) 2016-11-08 — — US disclosed
US-20160046863-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-02-18 — — US disclosed
US-20160046863-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-02-18 — — US disclosed
EP-2985334-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2016-02-17 — — EP disclosed
EP-2848676-A2 Liquid crystal medium Merck Patent GmbH (DE) 2015-03-18 — — EP disclosed
US-20150070609-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2015-03-12 — — US disclosed
US-20150070609-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2015-03-12 — — US disclosed
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