Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.84 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19138891 | 1.00 | HDAC6 (0.84) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL19162246 | 0.91 | HDAC6 (1.00) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL17500213 | 0.91 | HDAC6 (1.00) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL24011801 | 0.91 | HDAC6 (0.79) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL19139000 | 0.90 | HDAC6 (0.78) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL19162236 | 0.90 | HDAC6 (0.78) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL19138920 | 0.90 | HDAC6 (0.84) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL19162239 | 0.89 | HDAC6 (0.83) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL19138897 | 0.89 | HDAC6 (0.83) | HDAC6HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL19138914 | 0.88 | HDAC6 (0.87) | HDAC6HDAC4HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177621-B1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIV REGENSBURG (DE) | 2021-11-10 | — | — | EP | disclosed |
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universitätsklinikum Jena (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universitätsklinikum Jena (DE) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | HDAC6, HDAC5, HDAC4 | HDAC6 1/4885HDAC4 3/4885HDAC1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.