SCHEMBL1916650

SCHEMBL1916650

C/C=C/C=C/CC/C=C/C(=O)NCCC

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.60
CNR1 P21554 11/20 0.60
TRPA1 O75762 1/20 0.60
TRPV1 Q8NER1 1/20 0.60
PPARG P37231 3/20 0.55
PPARD Q03181 3/20 0.55
PPARA Q07869 3/20 0.55
FAAH O00519 1/20 0.40
SOAT1 P35610 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1916445 1.00 CNR2 (0.60) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL1916306 1.00 CNR2 (0.60) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL1916808 1.00 CNR2 (0.60) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL1917222 0.86 PPARG (0.64) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL1918394 0.86 PPARG (0.64) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL1916796 0.86 PPARG (0.64) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL1916581 0.86 PPARG (0.64) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL9943892 0.81 TAS1R3 (0.53) CNR2CNR1TRPA1TRPV1FAAH
SCHEMBL4406724 0.80 CNR1 (0.45) CNR2CNR1TRPA1TRPV1PPARG
Spilanthol SCHEMBL1916339 0.78 CNR2 (0.88) CNR2CNR1TRPA1TRPV1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2158894-B1 Oral cleansing agent HENKEL AG & CO KGAA (DE) 2018-11-07 EP disclosed
EP-2140853-B1 Coated particle for use in cosmetics HENKEL AG & CO KGAA (DE) 2018-07-18 EP disclosed
EP-2347754-B1 Oral and tooth care and cleaning agents with alkylpyridinium salts I HENKEL AG & CO KGAA (DE) 2018-01-24 EP disclosed
EP-2347753-B1 Oral and tooth care and cleaning agents with alkylpyridine salts II HENKEL AG & CO KGAA (DE) 2016-12-28 EP disclosed
EP-1935397-B1 Oral and tooth care and cleaning agents for combating halitosis HENKEL AG & CO KGAA (DE) 2016-03-02 EP disclosed
EP-2025319-B1 Numbing oral and tooth care and cleaning agents HENKEL AG & CO KGAA (DE) 2015-09-23 EP disclosed
EP-1774954-B1 Mouthwash and dentifrice and cleansing composition HENKEL AG & CO KGAA (DE) 2014-08-13 EP disclosed
EP-1806126-B1 Dental preparations comprising enzymes HENKEL AG & CO KGAA (DE) 2014-06-04 EP disclosed
EP-2476406-A2 Oral and tooth care and cleaning agents with improved antibacterial effect II Henkel AG & Co. KGaA (DE) 2012-07-18 EP disclosed
EP-2462916-A2 Oral and tooth care and cleaning agents with improved antibacterial effect I Henkel AG & Co. KGaA (DE) 2012-06-13 EP disclosed
EP-2025319-A2 Numbing oral and tooth care and cleaning agents Henkel AG & Co. KGaA (DE) 2009-02-18 EP disclosed
EP-1935397-A1 Oral and tooth care and cleaning agents for combating halitosis Henkel AG & Co. KGaA (DE) 2008-06-25 EP disclosed
EP-1880705-A2 Brightening and/or colouring composition with improved product sensation HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-01-23 EP disclosed
EP-1842573-A2 Brightening and/or colouring agent with improved product sensation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-10-10 EP disclosed
EP-1806124-A1 Dental preparations comprising enzymes HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-07-11 EP disclosed
EP-1806126-A1 Dental preparations comprising enzymes HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-07-11 EP disclosed
EP-1774953-A2 Mouthwash concentrate Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP disclosed
EP-1774956-A2 Mouthwash and dentifrice and cleansing composition Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP disclosed
EP-1774955-A2 Ready-to-use mounthwash Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP disclosed
EP-1774954-A2 Mouthwash and dentifrice and cleansing composition Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP disclosed