Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941604 | 0.85 | SMN1; SMN2 (0.57) | CCNCCDK8MAPTKMT2ANOTUM | |
| SCHEMBL3944400 | 0.85 | KMT2A (0.55) | CCNCCDK8MAPTKMT2ANOTUM | |
| SCHEMBL16741218 | 0.82 | CCNC (0.47) | CCNCCDK8MAPTKMT2ANOTUM | |
| SCHEMBL27660501 | 0.82 | KMT2A (0.51) | CCNCCDK8MAPTKMT2AALOX15 | |
| SCHEMBL2009003 | 0.82 | ALOX15 (0.62) | CCNCCDK8MAPTNOTUMALOX15 | |
| SCHEMBL16741071 | 0.82 | CCNC (0.49) | CCNCCDK8MAPTKMT2AALOX15 | |
| SCHEMBL6067800 | 0.82 | TSHR (0.58) | CCNCCDK8MAPTCHRNB2CHRNA4 | |
| SCHEMBL28060686 | 0.82 | CCNC (0.46) | CCNCCDK8MAPTKMT2ANOTUM | |
| SCHEMBL3361224 | 0.81 | NOTUM (0.49) | CCNCCDK8MAPTNOTUMNAMPT | |
| SCHEMBL2087239 | 0.81 | MAPT (0.47) | CCNCCDK8MAPTKMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327766-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-12-02 | — | — | EP | disclosed |
| EP-2319919-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2327767-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-29 | — | — | EP | disclosed |
| EP-2327765-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-01 | — | — | EP | disclosed |
| EP-2327765-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327767-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327766-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2039762-A2 | Nitralases | Verenium Corporation (US) | 2009-03-25 | — | — | EP | disclosed |