SCHEMBL1917993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1917996	1.00	LMNA (0.35)	LMNASLC6A2CYP3A4CYP1A2RET
	SCHEMBL1918496	0.86	LMNA (0.35)	LMNASLC6A2CYP3A4CYP1A2RET
	SCHEMBL1918556	0.86	SRD5A1 (0.37)	LMNASLC6A2CYP3A4CYP1A2RET
	SCHEMBL4364540	0.86	SRD5A1 (0.37)	LMNASLC6A2CYP3A4CYP1A2RET
	SCHEMBL1918498	0.86	LMNA (0.35)	LMNASLC6A2CYP3A4CYP1A2RET
	SCHEMBL1918552	0.86	SRD5A1 (0.37)	LMNASLC6A2CYP3A4CYP1A2RET
	SCHEMBL1918425	0.83	HTR2B (0.45)	LMNASLC6A2CYP1A2CHRM2CHRM4
	SCHEMBL1918427	0.83	HTR2B (0.45)	LMNASLC6A2CYP1A2CHRM2CHRM4
	SCHEMBL11093221	0.82	CES1 (0.45)	LMNASLC6A2CYP3A4CYP1A2RET
	SCHEMBL21812503	0.81	TDP1 (0.46)	LMNASLC6A2CYP3A4CYP1A2RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.