Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.86 |
| ▸ | PDE4A | P27815 | 1/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.76 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | MAOB | P27338 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19183195 | 1.00 | ABCG2 (0.86) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL633045 | 0.92 | ABCG2 (0.97) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL633046 | 0.92 | ABCG2 (0.97) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29443572 | 0.89 | ABCG2 (1.00) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6907516 | 0.88 | ABCG2 (0.89) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6907522 | 0.88 | ABCG2 (0.89) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30504730 | 0.87 | ABCG2 (0.78) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6905391 | 0.87 | ABCG2 (0.78) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6902519 | 0.86 | ABCG2 (0.86) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31619678 | 0.86 | ABCG2 (0.86) | ABCG2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132135-A1 | ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-03 | — | — | WO | disclosed |