Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.89 |
| ▸ | XDH | P47989 | 1/20 | 0.80 |
| ▸ | PDE4A | P27815 | 1/20 | 0.78 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.78 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907516 | 1.00 | ABCG2 (0.89) | ABCG2XDHPDE4APDE4BPDE4C | |
| SCHEMBL633046 | 0.93 | ABCG2 (0.97) | ABCG2XDHPDE4APDE4BPDE4C | |
| SCHEMBL633045 | 0.93 | ABCG2 (0.97) | ABCG2XDHPDE4APDE4BPDE4C | |
| SCHEMBL21527708 | 0.89 | XDH (1.00) | ABCG2XDHMAPTMEN1MAPK1 | |
| SCHEMBL21527710 | 0.89 | XDH (1.00) | ABCG2XDHMAPTMEN1MAPK1 | |
| SCHEMBL19183195 | 0.88 | ABCG2 (0.86) | ABCG2XDHPDE4APDE4BPDE4C | |
| SCHEMBL19183196 | 0.88 | ABCG2 (0.86) | ABCG2XDHPDE4APDE4BPDE4C | |
| SCHEMBL31619678 | 0.88 | ABCG2 (0.86) | ABCG2XDHPDE4APDE4BPDE4C | |
| SCHEMBL6902519 | 0.88 | ABCG2 (0.86) | ABCG2XDHPDE4APDE4BPDE4C | |
| SCHEMBL6902513 | 0.88 | ABCG2 (0.86) | ABCG2XDHPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176471-A1 | Novel chalcone derivatives and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176471-A1 | Novel chalcone derivatives and pharmaceutical compositions comprising the same | PTGS1, PTGES2, PTGES | ABCG2 71/4885XDH 1167/4885PDE4A 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.