SCHEMBL19183459

SCHEMBL19183459

Cc1cccc(O)c1C(=O)/C=C/c1ccc2c(c1)OCO2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.64
▸ KMT2A Q03164 5/20 0.64
▸ L3MBTL1 Q9Y468 2/20 0.64
▸ MAPT P10636 11/20 0.61
▸ CYP2D6 P10635 5/20 0.61
▸ CYP3A4 P08684 4/20 0.61
▸ CYP2C19 P33261 3/20 0.61
▸ CYP2C9 P11712 2/20 0.61
▸ ALDH1A1 P00352 5/20 0.60
▸ RAB9A P51151 7/20 0.58
▸ HPGD P15428 4/20 0.58
▸ POLB P06746 1/20 0.58
▸ AR P10275 1/20 0.58
▸ NPC1 O15118 6/20 0.57
▸ SMN1; SMN2 Q16637 5/20 0.57
▸ KDM4E B2RXH2 4/20 0.57
▸ LMNA P02545 3/20 0.57
▸ PKM P14618 3/20 0.57
▸ CYP1A1 P04798 2/20 0.57
▸ CYP1A2 P05177 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19183460 1.00 MEN1 (0.64) MEN1KMT2AL3MBTL1MAPTCYP2D6
SCHEMBL30383506 1.00 MEN1 (0.64) MEN1KMT2AL3MBTL1MAPTCYP2D6
SCHEMBL7656609 0.87 MAPT (0.74) MEN1KMT2AMAPTCYP2D6CYP3A4
SCHEMBL7656614 0.87 MAPT (0.74) MEN1KMT2AMAPTCYP2D6CYP3A4
SCHEMBL31233074 0.87 MAPT (0.74) MEN1KMT2AMAPTCYP2D6CYP3A4
SCHEMBL30383986 0.87 MAPT (0.74) MEN1KMT2AMAPTCYP2D6CYP3A4
SCHEMBL25195990 0.83 MAPT (0.69) MEN1KMT2AL3MBTL1MAPTCYP2D6
SCHEMBL7654646 0.82 AR (0.68) MEN1KMT2AL3MBTL1MAPTCYP2D6
SCHEMBL7654653 0.82 AR (0.68) MEN1KMT2AL3MBTL1MAPTCYP2D6
SCHEMBL5138041 0.82 MAPT (0.81) MEN1KMT2AL3MBTL1MAPTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
US-20190008797-A1 ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-01-10 — — US disclosed
WO-2017132135-A1 ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-08-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MEN1 3367/4885KMT2A 2792/4885L3MBTL1 3658/4885
US-20190008797-A1 ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF ESRRG, GPER1, ESR2 MEN1 4505/4885KMT2A 4031/4885L3MBTL1 3603/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885L3MBTL1 2560/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885L3MBTL1 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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