Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 17/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19185063 | 0.84 | P2RX3 (0.35) | P2RX3 | |
| SCHEMBL10056928 | 0.83 | P2RX3 (0.55) | P2RX3 | |
| SCHEMBL19185057 | 0.81 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL19185188 | 0.81 | P2RX3 (0.41) | P2RX3ALDH1A1 | |
| SCHEMBL10056317 | 0.81 | P2RX3 (0.57) | P2RX3 | |
| SCHEMBL19185227 | 0.75 | P2RX3 (0.42) | P2RX3 | |
| SCHEMBL19185098 | 0.75 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL17590504 | 0.74 | P2RX3 (0.56) | P2RX3 | |
| SCHEMBL19185062 | 0.74 | P2RX3 (0.43) | P2RX3 | |
| SCHEMBL17590712 | 0.74 | P2RX3 (0.45) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718790-B2 | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |