Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978299 | 0.89 | PRCP (0.40) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL19186564 | 0.89 | PRCP (0.35) | PRCP | |
| SCHEMBL19607500 | 0.82 | PRCP (0.43) | PRCP | |
| SCHEMBL16541579 | 0.80 | PRCP (0.45) | PRCP | |
| SCHEMBL2708513 | 0.80 | PRCP (0.45) | PRCP | |
| SCHEMBL9977086 | 0.80 | RPS6KB1 (0.34) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL19792198 | 0.80 | PRCP (0.43) | PRCP | |
| SCHEMBL19209573 | 0.79 | MAPK13 (0.40) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL18080872 | 0.79 | MAPK13 (0.40) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL18301374 | 0.79 | CYP3A4 (0.43) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718807-B2 | Synthesis of antiviral compound | GILEAD PHARMASSET LLC (US) | 2017-08-01 | — | — | US | disclosed |