Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19186397 | 0.89 | PRCP (0.38) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL19607500 | 0.85 | PRCP (0.43) | PRCP | |
| SCHEMBL16541579 | 0.83 | PRCP (0.45) | PRCP | |
| SCHEMBL2708513 | 0.83 | PRCP (0.45) | PRCP | |
| SCHEMBL19792198 | 0.82 | PRCP (0.43) | PRCP | |
| SCHEMBL9977086 | 0.81 | RPS6KB1 (0.34) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL19339538 | 0.80 | PRCP (0.42) | PRCP | |
| SCHEMBL18080872 | 0.80 | MAPK13 (0.40) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL19209573 | 0.80 | MAPK13 (0.40) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL18301376 | 0.80 | CYP3A4 (0.43) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079744-A1 | METHOD OF PREPARATION FOR LEDIPASVIR AND DERIVATIVE THEREOF, AND INTERMEDIATE COMPOUND FOR PREPARATION OF LEDIPASVIR | SHANGHAI FOREFRONT PHARMACEUTICAL CO LTD (CN) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079744-A1 | METHOD OF PREPARATION FOR LEDIPASVIR AND DERIVATIVE THEREOF, AND INTERMEDIATE COMPOUND FOR PREPARATION OF LEDIPASVIR | POLI, SAMHD1, TYMP | PRCP 750/4885MAPK13 1227/4885MAPK12 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.