Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.59 |
| ▸ | CTSK | P43235 | 7/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15081620 | 0.93 | CTSC (0.61) | CTSCCTSK | |
| SCHEMBL14821844 | 0.90 | CTSC (0.52) | CTSCCTSK | |
| SCHEMBL16071001 | 0.88 | CTSC (0.62) | CTSCCTSKCTSLCTSBCTSF | |
| SCHEMBL19187306 | 0.86 | CTSC (0.59) | CTSCCTSK | |
| SCHEMBL14821944 | 0.85 | CTSC (0.61) | CTSCCTSK | |
| SCHEMBL19186963 | 0.85 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL19186767 | 0.85 | CTSC (0.57) | CTSCCTSK | |
| SCHEMBL15081667 | 0.85 | CTSC (0.57) | CTSCCTSKCTSLCTSBCTSF | |
| SCHEMBL19186949 | 0.85 | CTSC (0.57) | CTSCCTSK | |
| SCHEMBL19186686 | 0.84 | CTSC (0.57) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758398-B1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL]-2-AZABICYCLO [2.2.1]HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2017-08-02 | — | — | EP | disclosed |