Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.59 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15081712 | 0.93 | CTSC (0.61) | CTSCCTSK | |
| SCHEMBL14822140 | 0.88 | CTSC (0.56) | CTSCCTSK | |
| SCHEMBL19187220 | 0.88 | CTSC (0.59) | CTSC | |
| SCHEMBL14821844 | 0.86 | CTSC (0.52) | CTSCCTSK | |
| SCHEMBL19187226 | 0.86 | CTSC (0.59) | CTSCCTSK | |
| SCHEMBL19186949 | 0.85 | CTSC (0.57) | CTSCCTSK | |
| SCHEMBL19187160 | 0.84 | CTSC (0.60) | CTSC | |
| SCHEMBL14822349 | 0.84 | CTSC (0.62) | CTSC | |
| SCHEMBL14822154 | 0.83 | CTSC (0.43) | CTSCCTSK | |
| SCHEMBL19186963 | 0.82 | CTSC (0.58) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758398-B1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL]-2-AZABICYCLO [2.2.1]HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2017-08-02 | — | — | EP | disclosed |