Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947473 | 0.84 | ADRA1D (0.59) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL21311447 | 0.80 | TSHR (0.64) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL3331311 | 0.80 | HPGD (0.60) | SMN1; SMN2HPGDKMT2APOLBMEN1 | |
| SCHEMBL31432180 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL12172746 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL21311316 | 0.79 | RXFP1 (0.56) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL21311145 | 0.78 | SMN1; SMN2 (0.58) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL20097036 | 0.78 | SMN1; SMN2 (0.67) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL3183106 | 0.77 | POLB (0.59) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL162725 | 0.77 | POLB (0.59) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326633-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010030592-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-03-18 | — | — | WO | disclosed |