Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19882343 | 0.83 | GRM4 (0.31) | CNR1RIPK1 | |
| SCHEMBL19882341 | 0.82 | KMT2A (0.46) | MEN1KMT2ATDP1DRD2DRD4 | |
| SCHEMBL22328974 | 0.82 | RIPK1 (0.48) | DRD2DRD4CCR2ALDH1A1RIPK1 | |
| SCHEMBL18876819 | 0.80 | CNR1 (0.45) | MEN1KMT2ATDP1DRD2DRD4 | |
| SCHEMBL13036470 | 0.79 | MEN1 (0.47) | MEN1KMT2ATDP1DRD2DRD4 | |
| SCHEMBL17447486 | 0.78 | MEN1 (0.40) | MEN1KMT2ATDP1DRD2DRD4 | |
| SCHEMBL17447490 | 0.77 | CNR1 (0.58) | MEN1KMT2ATDP1DRD2DRD4 | |
| SCHEMBL19176845 | 0.77 | MEN1 (0.42) | MEN1KMT2ATDP1DRD2DRD4 | |
| SCHEMBL23502424 | 0.75 | MEN1 (0.41) | MEN1KMT2ATDP1DRD2DRD4 | |
| SCHEMBL17447489 | 0.75 | MEN1 (0.41) | MEN1KMT2ATDP1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2887952-B1 | ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2019-05-15 | — | — | EP | disclosed |
| EP-2888286-B1 | ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2018-02-21 | — | — | EP | disclosed |
| EP-2888257-B1 | HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-02 | — | — | EP | disclosed |