Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5624044 | 0.95 | CETP (0.46) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL14602933 | 0.94 | CETP (0.44) | CETP | |
| SCHEMBL19188652 | 0.89 | CETP (0.39) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL19189671 | 0.81 | CETP (0.33) | CETPPTGDR2 | |
| SCHEMBL19189315 | 0.80 | CETP (0.31) | CETP | |
| SCHEMBL19188554 | 0.80 | CETP (0.30) | CETP | |
| SCHEMBL1898493 | 0.80 | CETP (0.47) | CETP | |
| SCHEMBL4222283 | 0.80 | CETP (0.49) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL19188507 | 0.80 | CXCR3 (0.31) | CETP | |
| SCHEMBL5624969 | 0.80 | CETP (0.47) | CETPTBXA2RPTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848430-B1 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | Dr Reddys Laboratories Ltd (IN) | 2017-08-02 | — | — | EP | disclosed |