SCHEMBL19189656

SCHEMBL19189656

Cc1nc2cccc(N)c2c(=O)o1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.70
CTRB1 P17538 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282843 0.82 ELANE (1.00) ELANECTRB1
SCHEMBL26672043 0.79 ELANE (0.70) ELANECTRB1
SCHEMBL23881485 0.79 ELANE (0.70) ELANECTRB1
SCHEMBL4119409 0.79 ELANE (0.70) ELANE
SCHEMBL10660772 0.79 ELANE (0.70) ELANE
SCHEMBL13206696 0.77 ELANE (1.00) ELANE
SCHEMBL10069984 0.77 ELANE (0.66) ELANECTRB1
SCHEMBL4468051 0.76 ELANE (0.64) ELANECTRB1
SCHEMBL282876 0.74 ELANE (0.62) ELANE
SCHEMBL1353839 0.74 ELANE (0.50) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2991976-B1 SYNTHESIS OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL) PIPERIDINE-2,6-DIONE CELGENE CORP (US) 2017-09-20 EP disclosed
EP-3199532-A1 INTERMEDIATE FOR THE SYNTHESIS OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL)PIPERIDINE-2,6-DIONE Celgene Corporation (US) 2017-08-02 EP disclosed