Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 19/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.51 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853323 | 1.00 | AVPR1A (0.66) | AVPR1AKCNH2AVPR2OXTR | |
| SCHEMBL14844441 | 1.00 | AVPR1A (0.66) | AVPR1AKCNH2AVPR2OXTR | |
| SCHEMBL2539944 | 0.84 | AVPR1A (0.66) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL2540655 | 0.84 | AVPR1A (0.66) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL2539946 | 0.84 | AVPR1A (0.66) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL19189883 | 0.84 | AVPR1A (0.65) | AVPR1AKCNH2AVPR2OXTR | |
| SCHEMBL2542010 | 0.83 | AVPR1A (0.67) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL2542009 | 0.83 | AVPR1A (0.67) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL2546578 | 0.83 | AVPR1A (0.67) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5102063 | 0.82 | AVPR1A (0.80) | AVPR1AKCNH2AVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763997-B1 | CYCLOHEXYL-4H,6H-5-OXA-2,3,10B-TRIAZA-BENZO[E]AZULENES AS V1A ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2017-08-02 | — | — | EP | disclosed |