Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 20/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17011376 | 1.00 | MME (0.53) | MMEACE | |
| SCHEMBL20280997 | 0.91 | MME (0.55) | MMEACE | |
| SCHEMBL16930520 | 0.91 | MME (0.55) | MMEACE | |
| SCHEMBL18724752 | 0.89 | MME (0.47) | MME | |
| SCHEMBL15939008 | 0.88 | MME (0.62) | MME | |
| SCHEMBL2875545 | 0.88 | MME (0.62) | MME | |
| SCHEMBL17409558 | 0.88 | MME (0.46) | MMEACE | |
| SCHEMBL16942452 | 0.86 | MME (0.48) | MMEACE | |
| SCHEMBL16932435 | 0.86 | ACE (0.53) | MMEACE | |
| SCHEMBL16932436 | 0.86 | ACE (0.53) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199517-A1 | NEPRILYSIN INHIBITORS | Theravance Biopharma R&D IP, LLC (US) | 2017-08-02 | — | — | EP | disclosed |